Keratosis lichenoides chronica: case report
Keywords:
Keratosis lichenoides chronicaAbstract
Keratosis lichenoides chronica (KLC) or Nekam’s disease is a controversial rare dermatosis of unknown etiology. It is characterized by symmetrically arranged lichenoid linear and reticulate scaly plaques and hyperkeratotic papules most marked on extremities and buttocks and accompanied by facial lesions resembling seborrheic dermatitis.It usually affects adults between 20 to 40 years but children are affected occasionally. We report a case of middle-aged female showing chronic lichenoid plaques in a characteristic linear and reticulate fashion over buttocks and thighs with minimal pruritus, resistant to conventional treatment, and associated seborrheic dermatitis like eruption on face. KLC is a chronic and progressive disorder extending over many years and is very resistant to therapeutic approaches. Despite being a rare disorder, it is important to be familiar with KLC, which can be easily confused with koebner’s phenomena of lichen planus.References
Ghislain PD, De Bier A, Creusy C, Modiano P. Keratosis lichenoides chronica: report of a new case, with success of PUVA therapy. Dermatol Online J. 2001;7:4-8.
Breathnach SM.Lichen planus and lichenoid disorders. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook’s Textbook of Dermatology. 8th edn. Vol 2. Oxford: Wiley- Blackwell; 2010. p. 41.1-28.
Martins LCG, Horne M, Moreira DN, Follador I, Almeida VRP. Keratosis lichenoides chronica- case report. An Bras Dermatol. 2011;86:S148-51.
Adiflen E, Erdem O, Celipci S, Gurer MA. Easy to diagnose, difficult to treat: keratosis lichenoides chronica. Clin Exp Dermatol. 2008;35:47-50.
Masouye I, Saurat JH. Keratosis lichenoides chronica: the centenary of another Kaposi’s disease. Dermatology.1995;191:188-92.
Wozniacka A, Schwartz RA, Omulecki A, Lesiak A, Sysa- Jedrzejowska A. Keratosis lichenoides chronica: a diagnostic and therapeutic challenge. Clin Exp Dermatol.2006;31:48-50.
Margolis MH, Cooper GA, Johnson SA. Keratosis lichenoides chronica. Arch Dermatol.1984;120:1471-4.
Ruiz-MaldonadoR, Duran-McKinster C, Orozco-Covarrubias L, Saez-De-Oscariz M, Palacios-Lopez C. Keratosis lichenoides chronica in pediatric patients: a different disease?J Am Acad Dermatol.2007;56:S1-5.
Nijsten T, Mentens G, Lambert J. Vascular variant of Keratosis lichenoides chronica associated with hypothyroidism and response to tacalcitol and acitretin. Acta Derm Venereol.2002;82:128-30.
Demirci E, Boyvat A, Arica IE, Kocyigit P, Ozdemir E, Heper AO. Keratosis lichenoides chronica: marked response to PUVA in combination with acitretin. Acta Derm Venereol. 2005;85:552-3.
Muñoz-Santos C, Yébenes M, Romaní J, Luelmo J. Response of keratosis lichenoides chronica to efalizumab therapy.Arch Dermatol.2009;145:867-9.