Adult onset urticaria pigmentosa: a case report

Authors

  • Smitha Prabhu
  • Raghavendra Rao
  • H. Sripathi
  • Ranjini Kudva

Keywords:

Mastocytosis, urticaria pigmentosa, histamine, adult-onset

Abstract

Urticaria pigmentosa is a fairly indolent form of cutaneous mastocytosis, which is more prevalent in infants than in adults. Adult onset disease is usually supposed to be associated with systemic disease and has a propensity for polycythemia vera and leukaemia in a certain percentage, though regression has been reported in as many as 19% cases. A useful clue to diagnose indolent forms from malignant forms is that invariably there is thrombocytopenia with leukocytosis in malignant forms. We report an adult female with typical lesions of urticaria pigmentosa, proven by skin biopsy, who showed a good response to H1 and H2 receptor blockage treatment. separately without any benefit. To resolve this problem, a combination of liquid nitrogen cryotherapy along with phenol 88% was planned. After single session, the patient responded to this method with complete depigmentation without any complication. We suggest that the combination of liquid nitrogen cryotherapy and phenol 88% for depigmentation of remaining normal pigmented skin in universal vitiligo, can be safe and cost-effective. 

References

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Published

2016-12-24

How to Cite

1.
Prabhu S, Rao R, Sripathi H, Kudva R. Adult onset urticaria pigmentosa: a case report. J Pak Assoc Dermatol [Internet]. 2016Dec.24 [cited 2025Feb.9];19(2):115-7. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/523

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Section

Case Reports

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