Scrofuloderma: a common type of cutaneous tuberculosis. A case report
Keywords:
Scrofuloderma, tuberculosis, Mycobacterium, anti-tuberculous drugsAbstract
Scrofuloderma is a common type of cutaneous tuberculosis characterized by a bluish-red nodule overlying an infected lymph gland, bone or joint that breaks down to form an undermined ulcer with a granulating tissue at the base. Progression of the disease leads to irregular adherent masses, densely fibrous at some places while fluctuant and discharging at others. It heals with a characteristic puckered scarring at the site of infection. The disease is caused by Mycobacterium tuberculosis and common anti-tuberculous drugs are recommended for treatment. Many similar cases with additional features have been reported in foreign literature. We describe a case of this disorder along with review of literature.References
Tappeiner G. Tuberculosis and Infections with Atypical Mycobacteria. In: Wolff K, Goldsmith LA, Katz SI, et al., eds. Fitzpatrick’s Dermatology in General Medicine, 7th edn. New York: McGraw-Hill; 2008. p. 1768-78.
Yates VM, Rook GAW. Mycobacterial infections. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook’s Textbook of Dermatology, 7th edn. London: Blackwell Science; 2004. p. 28.1-28.39.
Meltzer SM, Nacy CA. Cutaneous Tuberculosis. Jan 28, 2009. Available from http://emedicine.medscape.com/artical/1105317-overview.
Ngan V. Cutaneous tuberculosis [Internet] Online December, 2006. Available from: http://www.dermnetnz.org/becterial/tuberculosis.html
Rajakumar D, Rosenberg AM. Mycobacterium tuberculosis monoarthritis in a child. Pediatr Rheumatol 2008; 6: 2-10
Tan WP, Tang MBY, Tan HH. Scrofuloderma from the acromioclavicular joint presenting as a chronic ulcer in an immunocompetent host. Singapore Med J 2007; 48: 243-5.
Dye C, Scheele S, Dolin P et al. Consensus statement. Global burden of tuberculosis, estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project. JAMA 1999; 282: 677-86.
Gopinathan R, Pandit D, Joshi J et al. Clinical and morphological variants of cutaneous tuberculosis and its relation to mycobacterium species. Indian J Med Microbiol 2001; 19: 193-6.
Padmavathy L, Rao L, Ethirajan N et al. Scrofuloderma: A clinicopathological and epidemiological study. Indian J Dermatol Venereol Leprol 1963; 29: 25-42
Karabudak O, Dogan B, Harmanyeri Y. Long-lasting scrofuloderma of hands and foot. Acta Derm Venereol 2007; 87: 91-2.
Bravo FG, Arenas R, Sigall DA. Actinomycosis, nocardiosis and actinomycetoma. In: Wolff K, Goldsmith LA, Katz SI, et al., eds. Fitzpatrick’s Dermatology in General Medicine, 7th edn. New York: McGraw-Hill. 2008. p. 1778-86.
Afzal A, Nadeem M, Aman S, Kazmi AH. Mycobacterium marinum infection. J Pak Assoc Dermatol 2009; 19: 48-51
Hartley M. Botryomycosis, pyoderma vegetans. [Internet] Online April, 2010. Available from: http://dermnetnz.org/bacterial/botryomycosis.html
Morton RS, Kinghorn GR, Kerdel-Vegas F. The treponematoses. Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook’s Textbook o f Dermatology, 7th edn. London: Blackwell Science; 2004. p. 30.1-30.36.
Fite D. Hidradenitis Suppurativa. [Internet] Online May, 2010. Available from: http://emedicine.medscape.com/article/762444-overview
