The comparison of dyslipidemia in patients with and without acne vulgaris

Authors

  • Zaira Aslam Department of Dermatology, KEMU/ Mayo Hospital, Lahore.
  • Faria Altaf Department of Dermatology, SIMS/ Services Hospital, Lahore.
  • Sadia Jabeen Department of Dermatology, KEMU/ Mayo Hospital, Lahore.
  • Wajieha Saeed Department of Dermatology, KEMU/ Mayo Hospital, Lahore.
  • Ghazala Butt Department of Dermatology, KEMU/ Mayo Hospital, Lahore
  • Bushra Bashir Department of Dermatology, AIMC/ Jinnah Hospital, Lahore.
  • Ijaz Hussain Department of Dermatology, KEMU/ Mayo Hospital, Lahore.

Keywords:

Acne vulgaris, Serum lipid levels, Dyslipidemia

Abstract

Objective Acne vulgaris (AV) is the most common skin disease worldwide. It affects pilosebaceous unit and leads to range of lesions. In acne patients the serum lipid levels are altered as compared to individuals without acne. The main objective of the study is to determine the association between dyslipidemia and acne vulgaris.   Methods This case control study was done in Dermatology Department, Mayo Hospital, Lahore between 16-10-2020 to 15-04-2021. Total 246 cases (123 acne patients and 123 controls) were enrolled by non-probability, consecutive sampling.   Results Among 123 cases; mean total cholesterol was 188.4±26.2 mg/dl in cases. Mean of TG was 189.8211±59.42884 (minimum was 119 and maximum was 305). Mean of LDL 153.3984±28.77007 (minimum was 120 and maximum was 290). Mean of HDL was 33.9106±8.24821 (minimum was 20 and maximum was 43). Among 123 controls; Mean Total cholesterol was 212.8±58.3 mg/dl in controls. Mean of TG was 163.4472±69.88916 (minimum was 109 and maximum was 352). Mean of LDL 137.3659±19.92620 ((minimum was 105 and maximum was 170). Mean of HDL was 40.4228±7.86047 (minimum was 29 and maximum was 50). Odds of having dylipidemia among cases were 1.9.   Conclusion BMI, LDL-C and Triglycerides were raised significantly in acne patients as compared to controls while HDL-C was markedly low in cases. Dyslipidemia found significant among cases as compared to controls. Acne patients of younger age, female gender and normal BMI were more likely to have dyslipidemia.  

References

Tan AU, Schlosser BJ, Paller AS. A review of diagnosis and treatment of acne in adult female patients. Clin Cosmet Investig Dermatol. 2018;4(2):56-71.

Elsaie ML. Hormonal treatment of acne vulgaris: an update. Clin Cosmet Investig Dermatol. 2016;9:241.

Zaenglein A.L., Pathy A.L., Schlosser B.J., Alikhan A., Baldwin H.E., Berson D.S. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2016;74(5):945–73.

Arora MK, Seth S, Dayal S, Trehan AS, Seth M. Serum lipid profile in female patients with severe acne vulgaris. Clinical laboratory. 2014;60(7):1201-5.

Abulnaja KO. Changes in the hormone and lipid profile of obese adolescent Saudi females with acne vulgaris. Braz J Med Biol Res. 2009;42(6):501-5.

Kataria U, Malik Y, Chhillar D, Divya. A prospective outpatient case control study of serum lipidprofile in acne vulgaris patients. Int Med J. 2017;4(9): 909-13.

Manzoor S, Rather S, Shahab-ud-din S, Sameen F, Aleem S, Jeelani S. Therelationship between blood lipid profile and acne in non-obese,non-PCOS patients. Int J Contemp MedRes 2016;3(4):1096-109.

Arora MK, Seth S, Dayal S. The relationship of lipid profile and menstrual cycle with acne vulgaris. Clin Biochem. 2010 2010 Sep 27;43(18):1415–20.

El-Akawi Z, Abdel-Latif N, Abdul-Razzak K, Al-Aboosi M. The relationship between blood lipids prolife and acne. J Health Sci. 2007;53(5):596–9.

da Cunha MG, Batista AL, Macedo MS, Machado Filho CD, Fonseca FL. Study of lipid profile in adult women with acne. Clin Cosmet Investig Dermatol. 2015 Aug 17;8:449-54.

Downloads

Published

2023-10-12

How to Cite

1.
Aslam Z, Altaf F, Jabeen S, Saeed W, Butt G, Bashir B, Hussain I. The comparison of dyslipidemia in patients with and without acne vulgaris. J Pak Assoc Dermatol [Internet]. 2023Oct.12 [cited 2025Apr.27];33(4):1365-9. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/2653

Issue

Section

Original Articles

Most read articles by the same author(s)

1 2 3 4 5 6 7 8 9 10 > >>