To determine the relationship of cutaneous leishmaniasis with deranged aminotransferases
Keywords:
Cutaneous leishmaniasis; Raised aminotransferasesAbstract
Objective The objective of study is to determine the relationship of Cutaneous Leishmaniasis (CL) with the derangement of aminotransferases. Methods A Prospective study was carried out in the dermatology outpatient department of Punjab Rangers Teaching Hospital for a period of six months from September 2022 to February 2023 on a group of 30 Rangers Soldiers deployed in Kashmore which is an endemic area of cutaneous leishmaniasis. The patients presenting with nonhealing plaques and ulcers who tested positive for LD bodies on slit skin smears were enrolled. Liver function tests of all the patients were done at the baseline and recorded. Patients with comorbidities, or who were previously on some other drugs were excluded from the study. Results Amongst our thirty enrolled patients, thirteen showed raised alanine and aspartate aminotransferases, four showed increased alanine aminotransferases (ALT) and two showed increased aspartate aminotransferases (AST) only, which makes 63.3% of our total sample size. Conclusion Derangement of alanine and asparate aminotransferrases were observed in patients with cutaneous leishmaniasis.References
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