Isolation and identification of fungal species in patients of recalcitrant tinea corporis and/or tinea cruris attending tertiary care hospital in Karachi
Keywords:
Dermatophytes, ; Antifungals, Recalcitrant casesAbstract
Abstract Background: Tinea corporis and Tinea cruris is one of the chief infection seen in dermatology clinics affecting every age and gender. The rapidly rising prevalence of superficial fungal infection in our population warrants mycological analysis to establish any change in the causative dermatophytic specie responsible for ticking up the number of the cases. Objective: To isolate and identify the fungal species in patients of recalcitrant tinea corporis and / or tinea cruris attending tertiary care hospital in Karachi. Methods: This Cross-sectional study was conducted in the Outpatient Department of Dermatology, Dow University Hospital, Karachi, Pakistan from 11th April 2022 till 10th October 2022. It comprised of 60 patients who had either received one complete course of oral antifungal treatment and had responded poorly to the therapy (identified on the basis of clinical response) and had a recurrence of disease after cure. The skin scrappings were collected from these patients and then microscopy and cultures were performed. Results: Out was 60 patients of Recalcitrant Tinea Corporis and /or T .cruris KOH mount was positive in 43 (71.6%) patients and the culture isolated and identified the causative species in 53 (88.3%) patients. T.Tonsurans account for about 33.3% of the cases followed by T. Mentagrophytes accounting for 15% of the patients. In 11.6 % of the patients isolated specie was T. Rubrum. Conclusion: Rise in the number of recalcitrant dermatophytosis could possibly due to change in the species causing dermatophytosis. Mycological analysis can help in identifying such species and facilitate in the treatment of these patients. Keywords: Dermatophytes, Antifungals, Recalcitrant cases.References
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