Combination of panthenol, madecassoside and niacinamide in multi-lamellar emulsion as postprocedural laser treatment

Authors

  • Adhika Ayu Lestari Dermatology and Venereology Department, Faculty of Medicine, Universitas Indonesia
  • Kara Adistri Dermatology and Venereology Department, Faculty of Medicine, Universitas Indonesia
  • Teguh Hopkop Dermatology and Venereology Department, Faculty of Medicine, Universitas Indonesia
  • Irma Bernadette S Sitohang Dermatology and Venereology Department, Faculty of Medicine, Universitas Indonesia

Abstract

Laser resurfacing procedure in dermatology involves creating superficial wound. Erythema, edema, and scaling are common and temporary side effects. We report three patients which were given topical combination cream containing panthenol, madecassoside, and niacinamide in multi-lamellar emulsion (MLE) following laser skin resurfacing procedure. The combination cream was given to two patients receiving Q-switched Nd:YAG (RevLite®, Cynosure®, Massachusetts, USA) laser treatment and one patient receiving fractional CO2 (Bioxel®, AMI Inc®, Seoul, South Korea) laser treatment. Erythema and edema diminish gradually in 7 days after treatment. This may be due to the anti-inflammatory effects of panthenol, madecassoside, and niacinamide. MLE also may contribute to repairing the damaged skin barrier after procedure, thus supporting the superficial wound healing. Topical combination consisting of panthenol, madecassoside, and niacinamide in MLE may ameliorate various side effects following laser procedures in dermatology. However, further research with better methodology and greater sample size is needed   Key words   Panthenol; Madecassoside; Niacinamide; Postprocedure; Laser treatment.

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Published

2023-07-02

How to Cite

1.
Lestari AA, Adistri K, Hopkop T, Sitohang IBS. Combination of panthenol, madecassoside and niacinamide in multi-lamellar emulsion as postprocedural laser treatment. J Pak Assoc Dermatol [Internet]. 2023Jul.2 [cited 2024Jul.13];33(2):706-10. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/2093

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Case Reports