The Correlation between Comorbid Factors and Xerosis Cutis in Elderly
Abstract
Background Xerosis cutis is a common skin condition in the elderly which can affect the quality of life. Impaired epidermal barrier function in xerosis cutis results in sensitive skin which is susceptible to irritants, allergens, and pathogens. Xerosis cutis may be an indicator of an individual's health status as it may occur in people with systemic diseases. This study was a retrospective study, that aimed to analyze the relationship between comorbid factors with xerosis cutis in the elderly. Methods The inclusion criteria for this study were patients diagnosed with xerosis cutis aged more than 60 years at Dermatology and Venereology Outpatient Clinic Dr. Soetomo General Academic Hospital Surabaya for a period of 2 years. Results There were 87 xerosis cutis patients out of 299 elderly patients (29.10%) who came to the Dermatology and Venereology Outpatient Clinic at Dr. Soetomo General Academic Hospital Surabaya over a period of 2 years. Pearson Chi-square statistical analysis of the correlation between hypertension and diabetes mellitus with the occurrence of xerosis cutis resulted in p values of 0.000 and 0.001, respectively. Conclusion This study showed that there was a significant correlation between hypertension and diabetes mellitus with the occurrence of xerosis cutis.References
Zahruddin A, Damayanti D. Penuaan Kulit: Patofisiologi dan Manifestasi Klinis. Berkala Ilmu Kesehatan Kulit dan Kelamin. 2018;30(3):208-15.
Amin R, Lechner A, Vogt A, Blume-Peytavi U, Kottner J. Molecular characterization of xerosis cutis: A systematic review. PLoS One. 2021;16(12):e0261253.
doi: 10.1371/journal.pone.0261253.
Hahnel E, Blume-Peytavi U, Trojahn C, Kottner J. Associations between skin barrier characteristics, skin conditions and health of aged nursing home residents: a multi-center prevalence and correlational study. BMC Geriatr. 2017;17(1):263.
doi: 10.1186/s12877-017-0655-5.
White-Chu EF, Reddy M. Dry skin in the elderly: complexities of a common problem. Clin Dermatol. 2011;29(1):37-42.
doi: 10.1016/j.clindermatol.2010.07.005.
Nair PA, Vora R. Association of systemic diseases with cutaneous dermatosis in elderly population: preliminary observation at a rural tertiary care centre. J Family Med Prim Care. 2015;4(1):74-8.
doi: 10.4103/2249-4863.152259.
Mekić S, Jacobs LC, Gunn DA, Mayes AE, Ikram MA, Pardo LM, Nijsten T. Prevalence and determinants for xerosis cutis in the middle-aged and elderly population: A cross-sectional study. J Am Acad Dermatol. 2019;81(4):963-969.e2.
doi: 10.1016/j.jaad.2018.12.038.
Legiawati L, Yusharyahya SN, Sularsito SA, Setyorini ND. Insidens Penyakit Kulit Di Divisi Dermatologi Geriatri Poliklinik Kulit Dan Kelamin Rumah Sakit Dr. Cipto Mangunkusumo Tahun 2008-2013. MDVI. 2017;44(1):20–6.
Görög A, Bánvölgyi A, Holló P. Characteristics of the ageing skin, xerosis cutis and its complications. Developments in Health Sciences (published online ahead of print 2022). 2022;4(4):77-80.
doi: 10.1556/2066.2021.00051.
Damayanti, D. Skin Aging and Basic Skin Care in Elderly. Berkala Ilmu Kesehatan Kulit dan Kelamin 2017;29(1):73–80.
doi: 10.20473/bikk.V29.1.2017.73-80.
Akarsu S, Ozbagcivan O, Ilknur T, Semiz F, Inci BB, Fetil E. Xerosis cutis and associated co-factors in women with prurigo nodularis. An Bras Dermatol. 2018;93(5):671-9.
doi: 10.1590/abd1806-4841.20187127.
Baumann L. Cosmeceuticals and skin care in dermatology. In Kang S, Amagai M, Bruckner AL, Enk AH, Margolis DJ, McMichael AM, et al. (eds). Fitzpatrick’s in General Medicine 9th ed. 2019. New York: The McGraw Hill Companies.
Chung BY, Um JY, Kim JC, Kang SY, Park CW, Kim HO. Pathophysiology and Treatment of Pruritus in Elderly. Int J Mol Sci. 2020;22(1):174.
doi: 10.3390/ijms22010174.
Endo JO, Wong JW, Norman RA, Chang ALS. Geriatric dermatology: Part I. Geriatric pharmacology for the dermatologist. J Am Acad Dermatol. 2013;68(4):521.e1-521.e10.
doi: 10.1016/j.jaad.2012.10.063.
Augustin M, Wilsmann-Theis D, Körber A, Kerscher M, Itschert G, Dippel M, Staubach P. Diagnosis and treatment of xerosis cutis - a position paper. J Dtsch Dermatol Ges. 2019;17 Suppl 7:3-33.
doi: 10.1111/ddg.13906.