An effective combined therapy of meglumine antimoniate and co-trimoxazole for cutaneous leishmaniasis: A study in Quetta City

Authors

  • Bilal Ahmed
  • Muhammad Iqbal Tareen
  • Ashok Kumar
  • Saira Baloch
  • Hazir Rehman
  • Zahid Mustafa
  • Abdul Malik Tareen

Keywords:

Cutaneous leishmaniasis, meglumine antimoniate, co-trimoxazole, combined therapy

Abstract

Objective To evaluate the efficacy of combined therapy of meglumine antimoniate and co-trimoxazole in cutaneous leishmaniasis (CL). Methods 180 patients with active lesions of CL, confirmed by fine needle aspiration cytology (FNAC) were treated with combined therapy of meglumine antimoniate (Glucantime) and co-trimoxazole (Septran) for 20 days. Results Out of 180 patients, 160 (88.9%) were cured. A few patients reported nausea, vomiting, glossitis, skin rashes and folate deficiency. Conclusion The combined therapy of meglumine antimoniate (Glucantime) and co-trimoxazole (Septran) is more effective than the previously reported combined therapies. 

References

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Published

2016-12-02

How to Cite

1.
Ahmed B, Tareen MI, Kumar A, Baloch S, Rehman H, Mustafa Z, Tareen AM. An effective combined therapy of meglumine antimoniate and co-trimoxazole for cutaneous leishmaniasis: A study in Quetta City. J Pak Assoc Dermatol [Internet]. 2016Dec.2 [cited 2025Apr.23];24(2):122-6. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/190

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