Keratoacanthoma, verruca vulgaris arising over porokeratosis of mibelli; A new association
Keywords:
Porokeratosis of Mibelli, Keratoacanthoma, Verruca VulgarisAbstract
Porokeratosis is a clonal expansion of keratinocytes. Among the neoplasms, squmous cell carcinoma (SCC) is the most commonly reported malignancy in porokeratosis. Porokeratosis of mibelli, keratoacanthoma and verruca vulgaris have association with human papilloma virus (HPV). We report here a case of keratoacanthoma, verruca vulgaris in a lesion of porokeratosis of mibelli.References
Sertznig P, von Felbert V, Megahed M. Porokeratosis: present concepts. J Eur Acad Dermatol Venereol 2012;26:404–12.
LeBoit PE , Burg G , Weedon D , Sarasain A , eds. World Health Organization Classifi cation of Tumours. Pathology and Genetics of Skin Tumours . Lyon: IARC Press, 2008: 1– 47.
Griffiths C, Barker J, Bleiker TO, Chalmers R, Creamer D, editors. Rook's textbook of dermatology. John Wiley & Sons; 2016 Feb 29.
Ferreira FR, Nogueira Santos LD, Nogueira Mendes Tagliarini FA, Lanzoni de Alvarenga Lira M. Porokeratosis of Mibelli: literature review and a case report. An Bras Dermatol 2013;88(6 Suppl. 1):179–82.
Dover JS, Phillips TJ, Burns DA. Disseminated superficial actinic porokeratosis: coexistence with other porokeratotic variants. Arch Dermatol 1986;122:887–9.
Chu AC, Teixeira F. Acquired disorders of epidermal keratinization. Rook's Textbook of Dermatology, Ninth Edition. 2016 Jul 15:1-34.
Sarma N, Boler AK, Bhattacharya SR. Familial disseminated plaque type porokeratosis with multiple horns and squamous cell carcinoma involving anal skin. Indian J Dermatol Venereol Leprol 2009;75:551.
Batalla A, Roson E, De la Torre C. Porokeratoma: A different entity or a variant of verrucous (hyperkeratotic) porokeratosis? Indian J Dermatol 2013;58:158.
Weedon D. Weedon’s Skin Pathology. 3rd ed. London: Churchill Livingstone Elsevier; 2010.
Cerroni L, Kerl H. Keratoacanthoma. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, editors. Fitzpatrick’s Dermatology in General Medicine. 7th ed. New York: McGraw Hill; 2008. p. 1049 53.
Janik JP, Bang RH. Traumatic keratoacanthoma arising in a 15 year old boy following a motor vehicle accident. Pediatr Dermatol 2006;23:448 50.
Hadley JC, Tristani Firouzi P, Florell SF, Bowen GM, Hadley ML. Case series of multiple recurrent reactive keratoacanthomas developing at surgical margins. Dermatol Surg 2009;35:2019:24.
13th Global Dermatologists Congress Human papilloma virus induced molecular pathogenesis of verruca vulgaris Satadal Das and Swami , Moscow, Russia, July 23- 24, 2018.
Bhunia D, Ghosh S, Rudra O, Biswas S, Agarwal M, Ghosh A. Keratoacanthoma arising over margin of porokeratosis of mibelli: A new association?. Indian Journal of Dermatology. 2016;61(1).
Li J , Wang K , Gao F , et al . Array comparative genomic hybridization of keratoacanthomas and squamous cell carcinomas: different patterns of genetic aberrations suggest two distinct entities. J Invest Dermatol 2012 ; 132 : 2060 – 6 .
Forslund O , DeAngelis PM , Beigi M , Schjolberg AR , Clausen OP . Identifi cation of human papillomavirus in keratoacanthomas. J Cutan Pathol 2003 ; 30 : 423 – 9 .
Esser AC, Pittelkow MR, Randle HW. Human papillomavirus isolated from transplant-associated porokeratoses of mibelli responsive to topical 5% imiquimod cream. Dermatologic surgery. 2006 Jun 1;32(6):858-61.