Pityriasis lichenoides is an immune reactionary self-limiting benign disease


  • Khalifa E. Sharquie Department of Dermatology, College of Medicine, University of Baghdad. Medical City Teaching Hospital.
  • Inas K. Sharquie Department of Microbiology & Immunology, College of Medicine, University of Baghdad, Baghdad, Iraq.


Pityriasis lichenoides, PLEVA, PLC, immune reaction, triggering factors.


Objective Pityriasis ichenoides consists of Pityriasis Lichenoides et Varioliformis Acuta and Pityriasis Lichenoides Chronica. It might resolve spontaneously and without important sequelae such as lymphoma. This study aims to evaluate the demographic and clinical pictures of both types of pityriasis lichenoides.  Methods This is a clinical descriptive study on a long-term basis, in which patients with a clinical picture of pityriasis lichenoides were collected during the period between 2012 and 2020. Any triggering factors before the onset of the disease were noted and biopsies for histopathological evaluation were carried out.  Results Fifty-six patients with pityriasis lichenoides were evaluated; no obvious triggering factors were elucidated in both types. The acute form consisted of 16 (80%) males and 4 (20%) females. Their age range was from 5 to30 years with a median of around 17years. All presented with acute generalized erythematous necrotic lesions with burning and itching, simulating chicken pox that left hyperpigmentation after recovery. The chronic form consisted of 36 cases. Their age range was from 3 to 12 years with a median of 7 years; 31 (86%) were males and 5 (13.8%) were females. All cases had a slow course of progression over months and years. Fourteen patients (38.8%) were seen with generalized non-itchy erythematous papules with mica-like scales whereas 24 (66.66%) presented with hypopigmented lesions.  Conclusion Both acute and chronic forms are self-limiting conditions that stay for weeks to years and remit spontaneously. They are considered as an immune reaction to specific triggering factors such as an infection.  


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How to Cite

Sharquie KE, Sharquie IK. Pityriasis lichenoides is an immune reactionary self-limiting benign disease. J Pak Assoc Dermatol [Internet]. 2022Apr.10 [cited 2024Jun.17];31(3):328-33. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/1612



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