Outcome of microneedling combined with 35% focal trichloroacetic acid peeling in post acne atrophic scars
Keywords:
Icepick and Boxcar scars, microneedling, trichloroacetic acid, outcomeAbstract
Objective To study the outcome of microneedling combined with 35% focal trichloroacetic acid peeling in post acne atrophic scars. Methods This study was conducted in department of dermatology, unit 1, Jinnah hospital, Lahore. A total of 90 patients with Goodman Baron grade 2, 3 & 4 post acne atrophic scars were included in the study. All patients were treated with microneedling alternating with trichloroacetic acid focal peel via CROSS technique at 2 weekly intervals. Results Combination therapy with microneedling followed by trichloroacetic acid peeling resulted in improvement of 1 grade in 93.3% patients with grade 3 and 4 post acne atrophic scars regardless of the age, gender, duration and type of scar and the baseline grade of scarring. There was statistically no significant difference in the frequencies of improvement across various subgroups of patients based on patient’s age (p-value=0.731), gender (p-value=0.461), duration of disease (p-value=0.777), type of scar (p-value=0.899) and baseline Goodman and Baron Grade (p-value=0.821). Conclusion Combination therapy of microneedling followed by trichloroacetic acid peeling resulted in improvement of 1 grade in 93.3% patients with grade 3 and 4 post acne atrophic scars. XMultiCopyPasteTime to upgrade, it’s free!Simply click on the top left of the extension and register to get access to 10 shortcuts. Your email will remain secure, but we might get in touch for your feedback! XMultiCopyPasteTime to upgrade, it’s free!Simply click on the top left of the extension and register to get access to 10 shortcuts. Your email will remain secure, but we might get in touch for your feedback! XMultiCopyPasteTime to upgrade, it’s free!Simply click on the top left of the extension and register to get access to 10 shortcuts. Your email will remain secure, but we might get in touch for your feedback!References
Tan J, Bhate K. A global perspective on the epidemiology of acne. Br J Dermatol. 2015; 172(3): 3-12.
Lynn D, Umari T, Dunnick C, et al. The epidemiology of acne vulgaris in late adolescence. 2016; 7: 13–25.
Jacob CI, Dover JS, Kaminer MS. Acne scarring: a classification system and review of treatment options. J Am Acad Dermatol. 2001; 45(1): 109-17.
Khunger N. Step by step chemical peels. Jaypee Brothers Medical Publishers (P) Ltd.; 2009.
Dewandre L, Tenenbaum A. Procedures in cosmetic dermatology series: chemical peels. Elsevier; 2011.
Agarwal N, Gupta LK, Khare AK, et al. Therapeutic response of 70% trichloroacetic acid CROSS in atrophic acne scars. Dermatol Surg 2015; 41(5): 597-604.
Bhardwaj D, Khunger N. An assessment of the efficacy and safety of cross technique with 100% TCA in the management of ice pick acne scars. Indian J Cutan Aesthet Surg. 2010; 3(2): 93-6.
Sachdeva S. CROSS technique with full strength TCA in the management of ice pick acne scars. J Cutan Aesthet Surg. 2011; 4(2): 160.
Garg S, Baveja S. Combination therapy in the management of atrophic acne scars. J Cutan Aesthet Surg 2014; 7(1): 18-23.
Li X., Galzote C., Yan X., Li L., Wang X. Characterization of Chinese body skin through in vivo instrument assessments, visual evaluations, and questionnaire: Influences of body area, inter-generation, season, sex, and skin care habits. Skin Res Technol. 2014; 20: 14–22
Pochi P.E., Strauss J.S. Endocrinologic control of the development and activity of the human sebaceous gland. J Invest Dermatol. 1974; 62: 191–201
Aust MC, Reimers K, Repenning C, et al. Percutaneous collagen induction: minimally invasive skin rejuvenation without risk of hyperpigmentation fact or fiction? Plast Reconstr Surg 2008; 122(5): 1553-63.
Gonzalez AC, Costa TF, Andrade Zd, Medrado AR. Wound healing - a literature review. An Brasil Dermatol 2016; 91(5): 614-20.
Bhate K, Williams HC. Epidemiology of acne vulgaris. Br J Dermatol 2013; 168(3): 474-85.
Basta-Juzbasic A. Current therapeutic approach to acne scars. Acta Dermatovenerol Croat 2010; 18(3): 171-5.
Abdel Hay R, Shalaby K, Zaher H, Hafez V, Chi CC, Dimitri S, et al. Interventions for acne scars. Cochrane Database Syst Rev 2016; 4: CD011946.
Rajar UD, Majeed R, Sheikh F, Sheikh I, Siddique AA, Kumar S. Scarring in acne patients--a study done at Isra University Hyderabad. J Pak Med Assoc 2009; 59(8): 525-7.
Rana S, Mendiratta V, Chander R. Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars-A randomized controlled trial. J Cosmet Dermatol 2017; 16(4): 454-9.
Saadawi AN, Esawy AM, Mohamed WE. Microneedling and glycolic acid peel for treatment of acne scar; comparative study. ZUMJ 2018; 24(1): 44-54.
Chae WS, Seong JY, Jung HN, et al. Comparative study on efficacy and safety of 1550 nm Er: Glass fractional laser and fractional radiofrequency microneedle device for facial atrophic acne scar. J Cosmet Dermatol 2015; 14(2): 100–6.
Lu Wen-li, Zhang Zhen, FEI Ye CX. Comparison of a fractional micro-plasma radio-frequency technology versus fractional ultrapulsed CO2 laser for the treatment of atrophic acne scars. Chinese J Dermatol 2012; 45(3): 165–8.
Puri N. Comparative study of dermaroller therapy versus trichloroacetic acid cross for the treatment of atrophic acne scars. J Pak Assoc Dermatol 2015; 25(2): 114-8.
Arora S. A study of efficacy of microdermabrasion in treatment of facial acne scars-original research. Int J Dent Med Sci 2014; 1(2): 11-9.
Garg S, Baveja S. Combination therapy in the management of atrophic acne scars. J Cutan Aesthet Surg 2014; 7(1): 18-23.
