PREVALENCE OF DERMATOPHYTES IN SUPERFICIAL SKIN INFECTIONS IN A TERTIARY CARE HOSPITAL

Authors

  • Shahida Kashif Liaquat college of Medicine and Dentistry.
  • Fakhur Uddin Department of Microbiology, BMSI, JPMC
  • Farhina Nasir Karachi Medical & Dental College
  • Shahid Zafar Liaquat college of Medicine and Dentistry
  • Shah Jabeen Fazaia Ruth Pfau Medical College
  • Suresh Kumar Jinnah Sind Medical University.

Abstract

  Objective  To determine the prevalence of dermatophyte in superficial skin infection in a tertiary care hospital. Methods  It was a cross sectional study and conducted in the Department of Microbiology, BMSI, JPMC, Karachi, in collaboration with the dermatology department. Total 310 skin samples were collected. Samples were processed for primary screening test potassium hydroxide solution wet mount. Sabouraud's dextrose agar with (cycloheximide and chloramphenicol) & without antibiotics and dermatophyte test media were used for culture. Results Data was analyzed using SPSS version 22. Out of the 310 skin samples, 79 (31.29%) were positive for the dermatophytes. In this study, dermatophytes were most common group of fungi responsible for superficial skin infection in the said tertiary care Hospital. About 23(7.4%) were non-dermatophytes. A total of 78(25.16%) accounted for yeast and 8(2.5%) were found to be mixed growth. Tinea capitis was found to be the most prevalent clinical type followed by tinea corporis and tinea ungium, respectively. Conclusion  This study reveals that children are most commonly affected and followed by the age group of 21-30 year. Tinea capitis is the most prevalent skin infection in the studied population. The known prevalence of dermatophytes (31.29%) in superficial skin infections should be considered an important factor when determining the causative factors of skin diseases. In addition to this, the derived results can be taken as a base for probing further in the topic. This will help in adopting a more targeted approach towards treating the superficial skin infections.  

Author Biographies

Shahida Kashif, Liaquat college of Medicine and Dentistry.

Senior LecturerDepartment of Pathology

Farhina Nasir, Karachi Medical & Dental College

Department of Pathology

Shahid Zafar, Liaquat college of Medicine and Dentistry

Assistant ProfessorDepartment of Pathology

Shah Jabeen, Fazaia Ruth Pfau Medical College

Assistant Professordepartment of Physiology

Suresh Kumar, Jinnah Sind Medical University.

Assistant ProfessorDepartment of Pathology

References

Abd Elmegeed A, Ouf S, Moussa T, Eltahlawi S. Dermatophytes and other associated fungi in patients attending to some hospitals in Egypt. Brazilian Journal of Microbiology. 2015;46(3):799-805.

Al Hasan M, Fitzgerald S, Saoudian M, Krishnaswamy G. Journal search results - Cite This For Me. Clinical and Molecular Allergy. 2004;2(1):5.

Ayanlowo O, Akinkugbe A, Oladele R, Balogun M. Prevalence of Tinea capitis infection among primary school children in a rural setting in south-west Nigeria. Journal of Public Health in Africa. 2014;5(1).

Bhatia V, Sharma P. Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India. SpringerPlus. 2014;3(1).

Das S, Goyal R, Bhattacharya S. Laboratory-based epidemiological study of superficial fungal infections. The Journal of Dermatology. 2007;34(4):248-253.

Eftekarjo, Y., Balal, A., Taghavi, M., Rahimi, Z., Nikaein, D. Epidemiology and prevalence of superficial fungal infections among dormitory students in Tehran, Iran. Journal of Mycology Research, 2015; 2(1): 49-54.

EI N. Dermatophytosis in Western Africa: A Review. Pakistan Journal of Biological Sciences. 2010;13(13):649-656.

Ellabib M, Khalifa Z, Kavanagh K. Dermatophytes and other fungi associated with skin mycoses in Tripoli, Libya. Mycoses. 2002;45 (3-4):101-104.

Guarner J, Brandt M. Histopathologic Diagnosis of Fungal Infections in the 21st Century. Clinical Microbiology Reviews. 2011;24(2):247-280.

Hawkins, D., & Smidt, A. Superficial Fungal Infections in Children. Pediatric Clinics of North America. 2014;61(2):443-455. doi: 10.1016/j.pcl.2013.12.003

Havlickova B, Czaika V, Friedrich M. Epidemiological trends in skin mycoses worldwide. Mycoses. 2008;51:2-15.

Hay RJ, Ashby HR, fungal infections in Griffth CE, Barker JR leikerT, Chalmers R . Cremors D, eds rooks Text book of dermatology. 2016

Kaushik N, Pujalte G, Reese S. Superficial Fungal Infections. Primary Care: Clinics in Office Practice. 2015;42(4):501-516.

Kemna M, Elewski B. A U.S. epidemiologic survey of superficial fungal diseases. Journal of the American Academy of Dermatology. 1996;35(4):539-542.

Oke, O., Onayemi, O., Olasode, O., Omisore, A., & Oninla, O. The prevalence and pattern of superficial fungal infections among school children in ile-ife, south-western nigeria. Dermatology Research and Practice. 2014:1-7. doi: 10.1155/2014/842917

Perea, S., Jose Ramos, M., Garau, M., Gonzalez, A., R. Noriega, A., & del Palacio, A. (2000). Prevalence and Risk Factors of Tinea Unguium and Tinea Pedis in the General Population in Spain. Journal of Clinical Microbiology, 38(9).

Rezaei-Matehkolaei A, Makimura K, Hoog SD, Shidfar MR, Zaini F, Eshraghian M, et al. Molecular epidemiology of dermatophytosis in Tehran, Iran, a clinical and microbial survey. Medical Mycology. 2013;51(2):203–7.

Daalen FVV, Kallen MC, C. M. A. Van Den Bosch, Hulscher MEJL, Geerlings SE, Prins JM. Clinical condition and comorbidity as determinants for blood culture positivity in patients with skin and soft-tissue infections. European Journal of Clinical Microbiology & Infectious Diseases. 2017Jul;36(10):1853–8.

White TC, Findley K, Dawson TL, Scheynius A, Boekhout T, Cuomo CA, et al. Fungi on the Skin: Dermatophytes and Malassezia. Cold Spring Harbor Perspectives in Medicine. 2014Jan; 4(8).

Downloads

Published

2022-04-10

How to Cite

1.
Kashif S, Uddin F, Nasir F, Zafar S, Jabeen S, Kumar S. PREVALENCE OF DERMATOPHYTES IN SUPERFICIAL SKIN INFECTIONS IN A TERTIARY CARE HOSPITAL. J Pak Assoc Dermatol [Internet]. 2022Apr.10 [cited 2024Jun.17];31(3):484-8. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/1541

Issue

Section

Original Articles