Prevalence of metabolic syndrome among psoriatic patients attending a tertiary care hospital in Western India
Keywords:
Psoriasis, PASI, metabolic syndromeAbstract
Context Psoriasis is a multi-system inflammatory disease where the skin, nails and joints are commonly affected. Psoriasis is associated with an increased risk of cardiovascular atherosclerosis. Metabolic syndrome is a significant predictor of atherosclerotic disease with associated risk for cardiovascular events in such patients. Aim To study the prevalence of metabolic syndrome among psoriatic patients attending tertiary care hospital in western India. Material and Methods The present one year hospital based cross sectional study was done on a total of 100 psoriatic patients who attended our tertiary care hospital in western India from January 2017 to December 2017. A written consent form was obtained. All the patients were screened for metabolic syndrome according to NCEP-ATP III criteria. Venous samples were taken at the enrolment visit after the subjects had fasted overnight for measuring serum cholesterol, triglycerides and plasma glucose. An ethical committee clearance was obtained prior to the start of the study. Statistical analysis used: SPSS-17 software and epi-info software. Results In our study, 32 out of 100 psoriatic patients (32%) had metabolic syndrome. 69% of the study population were males and 31% were females. PASI <9 was seen in 64% of the population. Hypertension, diabetes mellitus, duration of the disease, PASI were statistically significant in relation to occurrence of metabolic syndrome. Conclusion Patients with psoriasis should be routinely screened for metabolic syndrome and treated accordingly to manage cardio-metabolic risk. However, the directionality of this association could not be established. Limitation; lack of controls in our study. Key message Early detection of metabolic syndrome can prevent the occurrence of cardiovascular abnormalities.References
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