Effect of 30% salicylic acid peels in mild to moderate acne vulgaris: a hospital-based nonrandomised clinical study

Authors

  • Bava Aneesh Pariyaram medical college Kannur, Kerala India 670503
  • Joy Bifi Pariyaram medical college Kannur, Kerala India 670503
  • Anoop Thyvalappil Pariyaram medical college Kannur, Kerala India 670503
  • Sridharan Rajiv Pariyaram medical college Kannur, Kerala India 67050
  • Sreenivasan Ajayakumar Pariyaram medical college Kannur, Kerala India 67050
  • mathew pretty Pariyaram medical college Kannur, Kerala India 67050

Keywords:

Acne vulgaris, chemical peel, salicylic acid

Abstract

Objective To study the effect of 30% salicylic acid peels in mild to moderate acne. Methods  The study was conducted on patients visiting the dermatology outpatient department of a tertiary health care centre in South India. In 50 cases of mild to moderate acne vulgaris, 30%  salicylic acid was applied in a predetermined manner for 5 minutes. Patients were reviewed once in two weeks up to 6 weeks with 3 sessions of peeling. Percentage reduction in acne severity index and total lesion count were noted to grade the effect of salicylic acid peel. Data collected was tabulated in a Microsoft Excel worksheet and a computer based analysis of the data was performed using SPSS software paired t test. Results By the end of 6 weeks, excellent improvement in  acne severity index was noted in 60% of cases and very good improvement in 30%. By the end of 6 weeks, excellent improvement in  total lesion count was noted in 60% and very good improvement in 34%. Conclusion Our study showed excellent to good improvement in most of patients. Our study showed that 30% salicylic acid peels can be considered as an important adjuvant therapy in mild to moderate acne with faster clinical response.

References

Cunliffe WJ, Gould DJ. Prevalence of facial acne vulgaris in late adolescence and in adults. Br Med J. 1979;1:1190-1200.

Gupta AK, Nicol K. The use of sulphur in dermatology. J Drugs Dermatol. 2004;3:427-31.

Savant SS, editor. Textbook of Dermatosurgery and Cosmetology, 2nd edn. Mumbai: ASCAD; 2005. p. 177-95.

Brody H, editor. Chemical Peeling and Resurfacing, 2nd edn. St. Louis: Mosby Year Book; 1997. p. 1-5.

Stegman SJ. A comparative histologic study of the effects of the three peeling agents and dermabrasion on normal and sun damaged skin. Aesth Plast Surg. 1982;6:123-35.

Kligman D, Kligman AM. Salicylic acid peels for the treatment of photoaging. Dermatol Surg. 1998;24:325-8.

Lee HS, Kim IH. Salicylic acid peels for treatment of acne vulgaris in Asian patients. Dermatol Surg. 2003;29:1196-9.

Burke BM, Cunliffe WJ. The assessment of acne vulgaris: The Leeds technique. Br J Dermatol. 1984;111:83-92.

Grimes PE. The safety and efficacy of salicylic acid peels in darker racial ethnic groups. Dermatol Surg. 1999;25:18-22.

Pearl A, Arnold B, Birchal NM, Birchall NM. The impact of acne: a study of adolescent attitudes, perceptions and knowledge. NZ Med J. 1998;111:265-71.

Green J, Sinclair RD. Perceptions of acne vulgaris in final year medical student written examination answers. Austral J Dermatol. 2001;42:98-101.

Cohen BA, Prosen P, Schachner AL. Acne. In: Schachner AL, Hansen CR, editors. Paediatric Dermatology, 2nd edn, Vol 2. New York: Churchill Livingstone; 1995. p. 661-83.

Khanna VN, Pandhi KR. Relationship of acne with menstrual period. Indian J Dermatol Venereol Leprol. 1991;57:138-40.

Smith RN, Mann NJ, Braue A, Mäkeläinen H, Varigos GA. A low glycemic load diet improves symptoms in acne vulgaris patients: a randomized controlled trial. Am J Clin Nutr. 2007;86:107-15.

Adebamowo CA, Spiegelman D, Berkey CS, Danby FW, Rockett HH, Colditz GA et al. Milk consumption and acne in adolescent girls. Dermatol Online J. 2006;12:1.

Hashimoto Y, Suga Y, Mizuno Y, Hasegawa T, Matsuba S, Ikeda S et al. Salicylic acid peels in polyethylene glycol vehicle for treatment of comedogenic acne in Japanese patients. Dermatol Surg. 2008;34:267-9.

Garg VK, Sinha S, Sarkar R. Glycolic acid peels versus salicylic mandelic acid peels in active acne vulgaris and post acne scarring and hyper pigmentation: A comparative study. Dermatol Surg. 2009;35:59-65.

Kessler E, Flanagan K, Chia C, Rogers C, Glaser DA. Comparison of alpha and beta hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris. Dermatol Surg. 2008;34:45-50.

Rendon MI, Berson DS, Cohen JL, Roberts WE, Starker I, Wang B. Evidence and considerations in the application of chemical peels in skin disorders and aesthetic resurfacing. J Clin Aesthet Dermatol. 2010;7:32-43.

Shalita AR. Treatment of mild to moderate acne vulgaris with salicylic acid in an alcohol-detergent vehicle. Cutis. 1981;28(5): 556-8.

Joshi SS, Boone SL, Alam M, Yoo S, White L, Rademaker A et al. Effectiveness, safety, and effect on quality of life of topical salicylic acid peels for treatment of post inflammatory hyper pigmentation in dark skin. Dermatol Surg 2009; 35(4): 638-44

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Published

2018-12-13

How to Cite

1.
Aneesh B, Bifi J, Thyvalappil A, Rajiv S, Ajayakumar S, pretty mathew. Effect of 30% salicylic acid peels in mild to moderate acne vulgaris: a hospital-based nonrandomised clinical study. J Pak Assoc Dermatol [Internet]. 2018Dec.13 [cited 2024Mar.28];28(2):146-51. Available from: http://www.jpad.com.pk/index.php/jpad/article/view/1096

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