Papillon-Lefevre syndrome: case report
Keywords:
Papillon–Lefevre syndromeAbstract
Papillon-Lefevre syndrome (PLS) is a rare genodermatosis of autosomal recessive inheritance manifesting as palmoplantar hyperkeratosis with periodontitis. A 4-year old Iranian girl was referred to the Mazandaran University Hospital, Sari complaining of well-demarcated, psoriasiform, yellowish, keratotic plaques over the skin of her palms and soles with transgrediens. For cutaneous lesions, she was treated with oral acitretin 0.5 mg⁄kg⁄day and topical keratolytic 5% salicylic acid in combination with 10% urea.References
Jain V, Gupta R, Prakash H. Prosthodontic rehabilitation in Papillon-Lefevre syndrome: A case report. J Indian Soc Pedod Prev Dent. 2005;23:96-8.
Gorlin RJ, Sedano H, Anderson VE. The syndrome of palmar plantar hyperkeratosis and premature periodontal destruction of the teeth. J Pediatr. 1964;65:895-908.
Cury VF, Costa JE, Gomez RS, Boson WL, Loures CG, De ML. A novel mutation of cathepsin C gene in Papillon-Lefevre syndrome. J Periodontol. 2002;73:307-12.
Haneke E. The Papillon-Lefèvre syndrome: keratosis palmoplanta1. ris with periodontopathy. Report of a case and review of the cases in the literature. Hum Genet. 1979;51:1-35.
Fischer J, Blanchet-Bardon C, Prud’homme J-F. Mapping of Papillon-Lefèvre syndrome to the chromosome 11q14 region. Eur J Hum Genet. 1997;5:156-60.
Laas MW, Hennies HC, Preis S, Stevens HP, Jung M, Leigh IM et al. Localization of a gene for Papillon–Lefèvre syndrome to chromosome 11q14-q21 by homozygosity mapping. Hum Genet. 1997;101:376-82.
D’Angelo M, Margiotta V, Ammatuna P, Sammartano F. Treatment of prepubertal periodontitis. A case report and discussion. J Clin Periodontol. 1992;19:214-9.
Schroeder HE, Seger RA, Keller HU, Rateitschak-Pluss EM. Behavior of neutrophilic granulocytes in a case of Papillon-Lefevre syndrome. J Clin Periodontol. 1983;10:618-35.
Dhanrajani PJ. Papillon-Lefevre syndrome: clinical presentation and a brief review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;108:e1-7.
Ullbro C, Crossner CG, Nederfors T, Alfadley A, Thestrup-Pedersen K. Dermatologic and oral findings in a cohort of 47 patients with Papillon-Lefèvre syndrome. J Am Acad Dermatol. 2003;48:345-51.
Papillon MM, Lefevre P. Deux Cas de keratodermie palmaire et plantaire symmetrique femial (maladie de Meleda) Chez la frere et al soeur; eoexistance clams les deux cas d alteratations dentaires graves. Bull Soc Derma Symp. 1924;31:82-7.
Mahajan VK, Thakur NS, Sharma NL. Papillon-Lefevre syndrome. Indian Pediatr. 2003;40:197-200.
Hall RK, editor. Paediatric Orofacial Medicine and Pathology, 1st ed. London: Chapman and Hall Medical; 1994.
Sagllie FR, Marfany A, Camargo P. Intragingival occurrence of Actinobacillus actinomycetemcomitans and Bacteroides gingivalis in active destructive periodontal lesions. J Periodontol 1988;59:259-65.
Stabholz A, Taichman S, Soskolne WA. Occurrence of Actinobacillus actinomycetemcomitans and anti-leukotoxin antibodies in some members of an extended family affected by Papillon-Lefevre syndrome. J Periodontol. 1995;66:653-7.
Kurban M, Wajid M, Shimomura Y, Bahhady R, Kibbi AG, Christiano AM. Evidence for a founder mutation in the cathepsin C gene in three families with Papillon-Lefèvre syndrome. Dermatology. 2009;219:289-94.
Rattan SK. Papillon-Lefevre syndrome in two brothers. Indian J Dermatol Venereol Leprol. 2002;68:155-6.
Hattab FN, Amin WM. Papillon-Lefèvre syndrome with albinism: 4. a review of the literature and report of 2 brothers. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100:709-16.
Haim S, Munk J. Keratosis palmoplantaris congenita with periodontosis, arachnodactyly and peculiar deformity of terminal phalanges. Br J Dermatol. 1965;77:42-54.
Meade JL, de Wynter EA, Brett P, Sharif SM, Woods CG, Markham AF et al. A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme activation and NK cell cytolytic activity. Blood. 2006;107:3665-8.
Tanaka I, Abe K, Shizukuishi T, Sakaguchi M, Aizawa T, Narata M et al. Papillon-Lefèvre syndrome with pyogenic liver abscess: case report focusing on radiological findings and review of the literature. Acta Gastroenterol Belg. 2008;71:429-30.
Anuradha S, Agarwal SK, Singh NP, Gupta A, Chowdhury V. An unusual presentation of the Papillon-Lefevre syndrome as recurrent liver abscesses. J Assoc Physicians India. 2002;50:974-6.
Khandpur S, Reddy BSN. Papillon-Lefevre syndrome with pyogenic hepatic abscess: A rare association. J Pediatr Dermatol. 2001;18:45-7.
Kreyden OP. Rare forms of hyperhidrosis. Curr Probl Dermatol. 2002;30:178-87.
Nakajima K, Nakano H, Takiyoshi N, Rokunohe A, Ikenaga S, Aizu T et al. Papillon-Lefevre syndrome and malignant melanoma. A high incidence of melanoma development in Japanese palmoplantar keratoderma patients. Dermatology. 2008;217:58-62.
Hacham-Zadeh S, Goldberg L. Malignant melanoma and Papillon-Lefevre syndrome. Arch Dermatol. 1982;118:2.
Haneke E: The Papillon-Lefevre syndrome: keratosis palmoplantaris with periodontopathy. Report of a case and review of the cases in the literature. Hum Genet. 1979;51:1-35.
Glenwright HD, Rock WP. Papillon-Lefevre syndrome. A discussion of etiology and a case report. Br Dent J. 1990;168:27-9.
