Frequency of undiagnosed diabetes mellitus in patient with herpes zoster
Keywords:
Diabetes mellitus, herpes zosterAbstract
Objective To determine frequency of undiagnosed diabetes mellitus in patients with herpes zoster. (HZ). Methods This cross-sectional study was performed at PNS Shifa hospital, Karachi from June, 2013 to December, 2013. A total of 89 patients suffering from HZ from age 40-70 years were included in this study after taking informed consent. All patients underwent fasting blood sugar evaluation from hospital laboratory. Results 34 (38.2%) patients were of 40-55 years of age while 55 (61.8%) were of 56-70 year age group. Mean age was 56.93±8.24 years, 48 (53.9) were male and 41 (46.1%) were females while undiagnosed diabetes mellitus in patients with HZ occurred in 36 (40.5%) while 53 (59. 5%) had no findings of the morbidity. Conclusion Frequency of undiagnosed diabetes mellitus is higher among patients with herpes zoster. So, it is recommended that every patient who present with HZ, should be evaluated for diabetes mellitus.ÂReferences
Shapiro M, Kvern B, Watson P et al. Update on herpes zoster vaccination: a family practitioner's guide. Can Fam Physician. 2011;57:1127-31.
Gialloreti LE, Merito M, Pezzotti P et al. Epidemiology and economic burden of herpes zoster and postherpetic neuralgia in Italy: a retrospective population-based study. BMC Infect Dis. 2010;10:230.
McDonald JR, Zeringue AL, Caplan L et al. Herpes zoster risk factors in a national cohort of veterans with rheumatoid arthritis. Clin Infect Dis. 2009;48:1364-71.
American Diabetic Association. Standards of medical care in diabetes. Diabetes Care. 211;34:S11.
Nassaji-Zavareh M, Taheri R, Ghorbani R, Aminian M. Undiagnosed diabetes mellitus in patients with herpes zoster. Indian J Dermatol. 2008;53:119-21.
Heymann AD. Diabetes as a risk factor for herpes zoster infection: results of a population-based study in Israel. Infection. 2008;36:226-30.
Ragozzino MW, Melton LJ, Kurland LT. Herpes zoster and diabetes mellitus: an epidemiological investigation. Chronic Dis. 1983;36:501-5.
Geerlings S, Hoepelman A. Immune dysfunction in patients with diabetes mellitus (DM). FEMS Immunol Med Microbiol. 1999; 26:259-65.
Diabetes Control and Complications Trial Research Group The effect of intensive diabetes therapy on the development and progression of neuropathy. Ann Intern Med. 1995;122:561-8.
Ragozzino M, Melton L, Kurland L et al. Population based study of herpes zoster and its sequelae. Medicine. 1982;61:310-6.
Brown GR. Herpes zoster: Correlation of age, sex, distribution, neuralgia and associated disorders. South Med J. 1976;69:576-8.
Cerny Z. Recurrent eruptions of herpes zoster. Bratisl Lek Listy. 1999;100:515-8.
Guidetti D, Gabbi E, Motti L, Ferrarini G. Neurological complications of herpes zoster. Ital J Neurol Sci. 1990;11:559-65.
Ragozzino MW, Melton LJ, Kurland LT. Herpes zoster and diabetes mellitus: an epidemiological investigation. Chronic Dis. 1983;36:501-5.
Bajaj DR, Devrajani BR, Yousfani A et al. Frequency and pattern of herpes zoster at Liaquat University Hospital Hyderabad (Six months hospital based descriptive study). J Liaquat Uni Med Health Sci. 2009;8:113-7.
