Rate of metabolic syndrome in psoriasis
Keywords:Psoriasis, metabolic syndrome
AbstractObjective To assess the rate of metabolic syndrome among the patients of psoriasis. Methods It was a hospital based cross-sectional study. Fifty-eight patients, clinically and histopathologically diagnosed as psoriasis were selected by purposive sampling. Data including age, waist circumference and arterial blood pressure were recorded. Fasting blood glucose, triglyceride and HDL levels were measured. Metabolic syndrome was diagnosed by the presence of three or more of the five criteria of the modified version of National Cholesterol Education Programs Adult Panel III (ATPIII). . Results Out of 58 patients, 17 (29.3%) patients had metabolic syndrome. The prevalence of metabolic syndrome was higher in psoriatic patients in the 4th decade of life and predominant in male subjects. In psoriatic patients with metabolic syndrome, raised waist circumference >90 cm in men or >80 cm in women was found in 14 (82.3%), HDL cholesterol ≤40 mg/dl in 13 (76.5%), blood pressure >130/85 mm Hg in 16 (94.1%), and fasting blood sugar >5.6 mmol/L was noticed in 12 (70.6%) patients. Conclusion Metabolic syndrome was diagnosed in 29.3% of the psoriatic patients. Waist circumference, serum HDL cholesterol, blood pressure and fasting blood sugar were statistically significantly different (p<0.05) between patients with metabolic syndrome and without metabolic syndrome.
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